Dr. Satya N.Das
Present Position:
Senior Consultant (Healthcare)
NERBPMC, DBT (Government of India)
Office Address:
A-258, First Floor, S. B. House, Defence Colony
New Delhi-110024
Telephone: 011-49507200;Fax-011-49507215.
ORCID id:
http://orcid.org/0000-0002-1659-2499Google scholar: https://scholar.google.co.in/citations?user=E5Q4FnoAAAAJ&hl=en
Citations: 1261, h-index: 21, i10-index: 44.
Education:
-M. Sc, Ph.D. (Banaras Hindu University, Varanasi).
Teaching & Research Experience:
Research->35 years, PG teaching in Medical Biotechnology/Immunology -25 years.
Professional career and positions held: :
| Position | Institutions | Year |
| Assistant Professor | Department of Biotechnology, All India Institute of Medical Sciences |
1992-1997 |
| Associate Professor | Department of Biotechnology, All India Institute of Medical Sciences |
1997-2001 |
| Additional Professor | Department of Biotechnology, All India Institute of Medical Sciences |
2001-2010 |
| Professor | Department of Biotechnology, All India Institute of Medical Sciences |
2010-2017 |
Visiting Fellowship:
| Visiting Scientist (DAAD) | DKFZ, Heidelberg, Germany | May-July, 1997 |
| Visiting Scientist | Institute of Molecular Biology and Biochemistry, FU, Berlin, Germany | June- Nov, 1999 |
| Visiting Scientist | DKFZ, Heidelberg, Germany | May-June, 2004 |
Research Training:
| Year | Description |
| 1984 | ‘Radioimmunoassay and Its Clinical Applications’, at Bhabha Atomic Research Centre, Trombay, Bombay. A certificate of competence was obtained. |
| 1986 | ‘Immunochemistry and its Application in Clinical Sciences’, at K.G. Medical College, Lucknow. A certificate of competence was obtained. |
| 1992 | ‘Training on Medical Education: Evaluation Strategies’, at the All India Institute of Medical Sciences, New Delhi, A certificate of competence was obtained. |
| 2001 | ' The Use of Expression Systems for Studying Structure, Function and Regulation of Membrane Proteins, ICRO-UNESCO, Shanghai, China, A certificate of Competence was obtained. |
Membership/Fellowship of Professional bodies:
- Fellow, National Academy of Medical Sciences
- Fellow, International Academy of Biological Therapy
- Member, National Academy of Medical Sciences, India
- Life Member, The Cytometry Society, India
- Life Member, Indian Immunology Society
- Member, American Association for Cancer Research, USA
- Member, DKFZ Alumni Association, Heidelberg, Germany
- Member, Heidelberg University Alumni Association, Germany
- Member, Alexander von Humboldt Foundation Alumni Association, Germany
Distinction/ Honours/ Awards:
| Year | Description |
| 1977-79 | Junior Research Fellowship (University Grant Commission) |
| 1979-81 | Senior Research Fellowship (University Grant Commission) |
| 1981-82 | Senior Research Fellowship (Indian Council of Medical Research) |
| 1997 | Awarded DAAD Fellowship under German Academic Exchange Program |
| 1997 | Best paper award from Indian Pediatric Surgery Association |
| 1998 | Nominated as a member of the Scientific Committee, 1st International Conference on Biological Therapy and Modern Cancer Treatment, Guangzhou and Hong Kong, China. |
| 1999 | Visiting Fellowship from the Institute of Molecular Biology and Biochemistry, Free University, Berlin, Germany. |
| 2000 | Elected as a Member of the National Academy of Medical Sciences, India. |
| 2001 | Awarded ICRO-UNESCO Visiting Fellowship. |
| 2002-2004 | Elected as a Member of the Executive Committee of the Indian Immunology Society, India. |
| 2003 | Elected as Member of the American Association for Cancer Research, USA. |
| 2004 | Awarded Visiting Fellowship from German Cancer Research Center (DKFZ), Heidelberg, Germany. |
| 2007 | Awarded travel grant from DKFZ Alumni Association, Heidelberg, to attend Indo-German Workshop at Heidelberg, Germany, July12-14, 2007. |
| 2008 | Best poster award in the National Conference on Genomics, Proteomics & Systems Biology, Bangalore (1-3 Oct. 2008). |
| 2008 | Member: Task-force group on Cancer Cervix (DBT), Task-force group to establish Normal range of Lymphocyte Sub-sets in Indian Population (ICMR, NACO, DBT). |
| 2008 | Member Editorial Board: Clinical Reviews and Opinions (Academic journals). |
| 2010 | Regular member of Doctoral Committee, Department of Medical Elementology and Toxicology, Jamia Hamdard University, New Delhi. |
| 2010 | Fellow, National Academy of Medical Sciences, India. |
| 2011 | Member Editorial Board, World Journal of Stomatology. |
| 2012 | Member, Task Force Group on Cancer Research, Department of Biotechnology, Govt. of India. |
| 2012 | Awarded certificate of Excellence for poster presentation in the international Conference, CARCINOGENESIS 2012, New Delhi, India, 19-21 Nov. 2012. |
| 2013 | Mukut Saharia Gold medal for best paper presented at 36th Annual Conference of Otolaryngologists of India (New Delhi, 27-28th April 2013). |
| 2014 | Awarded “Award of Honour” at Biotechon-2014, Baba Farid University of Health Sciences, Faridkot, Punjab. |
| 2014 | Unanimously Elected as Vice-President (North) of Indian Immunology Society for 2014-2016. |
| 2014 | ‘Certificate of Outstanding Contribution in Reviewing’ In recognition of the review made for the journal, by The Editors of CANCE LETTERS, Elsevier. |
| 2015 | ‘Certificate of Outstanding Contribution in Reviewing’ In recognition of the contributions made to the Quality of the journal, by The Editors of CANCE LETTERS, Elsevier. |
| 2015 | Conferred ‘APTI Appreciation Award’ by Association of Pharmaceutical Teachers of India (Himachal Pradesh Branch) in collaboration with Centre of Excellence in Research, Baba Farid University of Health Sciences, Faridkot (Punjab). |
| 2016 | Conferred ‘Award for Popularization of Science’ by University Centre of Excellence in Research, Baba Farid University of Health Sciences, Faridkot, Punjab, India. |
| 2016 | ‘Certificate of Reviewing’, In recognition of the review made for the journal by the Editor, Archives of Oral Biology, ELSEVIER, Amesterdam. |
| 2016 | ‘Certificate of Reviewing’, In recognition of the review made for the journal by the Editor, Cancer Letters, ELSEVIER, Amesterdam. |
| 2016 | ‘Certificate of Reviewing’, In recognition of the review made for the journal by the Editor, GENE, ELSEVIER, Amesterdam. |
| 2017 | Unanimously elected as Vice President (North zone) of Indian Immunology Society |
| 2017 | Member, Board of Studies in Medical laboratory Sciences, IKG Technical University, Kapurthala, Punjab. |
| 2017 | Member, Editorial Board, Cancer Research and Clinical Oncology Open Access |
| 2017 | Regional Editor,The Open Journal of Immunology (Bentham Open). |
Ph.D. Thesis Examiner of the following Institute/University (Ad-hoc):
Agra University, Agra; Birla Institute of Technology & Science, Pilani; Indian Institute of Pathology, New Delhi; Indian Institute of Toxicology Research, Lucknow; Jawahar Lal Nehru University, New Delhi; Jadavpur University, Kolkata Jamia Hamdard University, New Delhi; University of Delhi, Delhi; Pondicherry University, Pondicherry; Post Graduate Institute of Medical Education & Research, Chandigarh; University of Kerala, Thiruvananthapuram
Referee for Scientific Projects (Ad-hoc):
- Department of Biotechnology, Ministry of Science &
Technology
- Department of Science & Technology (SERC), Ministry of
Science & Technology
- Indian Council of Medical Research, Ministry of Health &
Family Welfare
- AYUSH, Ministry of Health & Family Welfare
- Kerala State Department of Science and Technology
Peer reviewer of following scientific journals (ad-hoc):
Anatomical Records; Archives of Oral Biology; Cancer Immunology & Immunotherapy; Cancer Investigations; Cancer Letters; Cellular and Molecular Immunology; Gene; Immunological Investigations; Indian Journal of Medical Research; International Journal of Immunogenetics; Journal of Biosciences
Journal of Cellular and Molecular Medicine; Journal of Oral Pathology and Medicine; Life Sciences; Molecular and Cellular Endocrinology; Oral Oncology; PloS ONE.
Major area: Medical Biotechnology (Immunology &
Molecular Biology), Oncology and Oncogenomics
Research interest: Genetics, Immunology and Molecular Biiology of cancer, Oral.Oncolog
No. of thesis guided as Chief/ Co-Supervisor (PG/Doctoral thesis): 106.
Research grants handled: 15; Total budget- 341.28 lakh.
Sources of Funding: Indian Council of Medical Research, Council of Scientific & Industrial Research, Department of Biotechnology (Ministry of Science & Technology), AYUSH, Department of Science & Technology), Government of India.
Total publications: 152 (Research papers/abstracts- 122, Books- 2, Book chapters- 25, Reports/ Monographs- 5).
Selected recent publications in journals (in reverse chronological order):
1. Gaur P, Shukla NK, Das SN (2017). Phenotypic and functional characteristics of Th17 (CD4+IL17A+) cells in human oral squamous cell carcinoma and its clinical relevance. Immunol Investig. 46(7):689-702. (IF 1.824)
2. Aggarwal S, Sharma SC, Das SN (2017). Dynamics of regulatory T cells (Tregs) in patients with oral squamous cell carcinoma. J. Surg. Oncol. DOI: 10.1002/jso.24782 ( IF 2.994)
3. Arora R, Bharti V, Gaur P, Aggarwal S, Mittal M, Das SN (2017). Operculina turpethum extract inhibits growth and proliferation by inhibiting NF-κB, COX-2 and cyclin D1 and induces apoptosis by up regulating P53 in oral cancer cells. Arch Oral Biol. 80:1-9. (IF 1.733)
4. Aggarwal S and Das SN (2016). Thiodigalactoside shows antitumor activity by beta-galactoside-binding protein and regulatory T cells inhibition in oral squamous cell carcinoma. Oral Di. 22: 445-453. (IF:2.66).
5. Kapoor V, Aggarwal S and Das SN. (2016). 6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest. Phytother Res 30:588-595 (IF:2.427).
6. Vallonthaiel AG, Singh MK, Dinda AK, Kakkar A, Thakkar A, Das SN (2016). Prognostic significance of P27 in oral squamous cell carcinoma. J Oral Pathol Med. 45:475-80 doi: 10.1111/jop.12392. (IF 1.859)
7. Aggarwal S, Das SN, Sharma SC (2016). Imbalance in regulatory T (Treg) cells frequency in peripheral circulation of patients with oral squamous cell carcinoma and their effects on growth of oral cancer. Cancer Immunol Res, 4: A068. (IF:3.857)
8. Aggarwal S, Das SN, Sharma SC (2015). Vascular endothelial growth factor (VEGF) expression in patients with oral squamous cell carcinoma and its effects on tumor cell growth. Mol Cancer Ther 14: A01. (IF: 5.683).
9. Aggarwal S and Das SN (2015). Garcinol inhibits tumour cell proliferation, angiogenesis, cell cycle progression and induces apoptosis via NF-κB inhibition in oral cancer. Tumor Biol 37(6):7175-84. (IF: 3.61)
10. Vallonthaiel AG1, Singh MK, Dinda AK, Kakkar A, Thakar A, Das SN(2016). Expression of Cell Cycle-associated Proteins p53, pRb, p16, p27, and Correlation With Survival: A Comparative Study on Oral Squamous Cell Carcinoma and Verrucous Carcinoma. Appl Immunohistochem Mol Morphol. 24(3):193-200. (IF: 2.01)
11. Kumar S, Kumar J, Singh K, Kapoor V, Sinha M, Xess I, Das SN, Sharma S, Singh TP, Dey S. (2015).Biological Properties and Characterization of ASL50 Protein from Aged Allium sativum Bulbs. Appl Biochem Biotech. 176(7):1914-27 (IF: 1.69).
12. Aggarwal S, Sharma SC, Das SN (2015). Galectin-1 and galectin-3: plausible tumour markers for oral squamous cell carcinoma and suitable targets for screening high-risk population. Clin Chim Acta 442: 13-21 (IF: 2.892).
13. Singh AK, Gaur P, Shukla NK, Das SN (2015). Differential dendritic cell-mediated activation and functions of invariant NKT cell subsets in oral cancer. Oral Dis. 21(1): e105-e113. (IF:2.377)
14. Kumar S, Kapoor V, Gill K, Singh K, Xess I, Das SN, Dey S.(2014) Antifungal and Antiproliferative Protein from Cicer arietinum: A Bioactive Compound against Emerging Pathogens. Biomed Res Int. 2014;2014:387203. (IF: 3.17).
15. Aggarwal S, Devaraja K, Sharma SC, Das SN. (2014). Expression of Vascular Endothelial Growth Factor (VEGF) in patients with oral squamous cell carcinoma and its clinical significance. Clin Chim Acta.436:35-40. (IF: 2.892)
16. Gaur P, Singh AK, Shukla NK, Das SN (2014). Inter-relation of Th1, Th2, Th17 and Treg cytokines in oral cancer patients and their clinical significance. Hum Immunol 75 (4): 330-337. (IF:2.732)
17 Singh AK, Gaur P, Das SN (2014). Natural Killer T cell anergy, co-stimulatory molecules and immunotherapeutic interventions. Hum Immunol. 75 (3):250-260 (doi 10.1016/ j.humimm . 2013.12.004 PMID:24373798). (IF: 2.732)
18. Singh AK, Shukla NK, Das SN (2013). Altered Invariant Natural Killer T cell subsets and functions in patients with oral squamous cell carcinoma. Scand J Immunol. 78: 468-477. (IF:2.27)
19. Jha R, Gaur P, Sharma SC and Das SN (2013) Single nucleotide polymorphism in hMLH1 promoter and risk of tobacco-related oral carcinoma in high-risk Asian Indians. Gene :526:223-227. (IF:2.341)
20. Bharti V, Mohanti BK, Das SN (2013). Functional genetic variants of CTLA-4 and risk of tobacco-related oral carcinoma in high-risk North Indian population. Hum Immunol 74: 348-352 (IF: 2.732).
21. Garg R, Kapoor, V, Mittal M, Singh MK, Shukla NK and Das SN (2013). Abnormal expression of PI3K isoforms in patients with tobacco-related oral squamous cell carcinoma. Clin Chim Acta. 416 (1): 100-106. (IF:2.892)
22. Karimi MY, Kapoor V, Sharma SC, Das SN (2013). Genetic polymorphisms in FAS (CD95) and FAS ligand (CD178) promoters and risk of tobacco-related oral carcinoma: gene-gene interactions in high-risk Indians. Cancer Invest . 31(1):1-6. (IF:1.857)
23. Singh AK, Shukla NK and Das SN (2012). Reduced frequency and impaired functional properties of CD3+ 6B11+ iNKT cells in patients with tobacco-related oral squamous cell carcinoma. J Carcinogenesis. 11 (Suppl.1) S25. (IF: 2.318)
24. Gill K, Singh AK, Kapoor V, Nigam L, Kumar R, Holla P, Das SN, Yadav S, Subbarao N, Mohanti BK, Dey S (2012). Development of peptide inhibitor as a therapeutic agent against Head and Neck Squamous Cell Carcinoma (HNSCC) targeting p38α MAP kinase. Biochim Biophys Acta. 1830(3):2763-2769. (IF: 5.083).
25. Gaur P, Qadir GA, Upadhyay S, Singh AK, Shukla NK, Das SN (2012): Skewed immunological balance between Th17 (CD4+IL17A+) and Treg (CD4+ CD25+ FOXP3+) cells in human oral squamous cell carcinoma. Cellular Oncol (Dordr). 35(5):335-43. (IF: 3.562)'
26. Kapoor V, Paliwal D, Singh SB, Mohanti BK, Das SN (2012). Deregulated expression of Beclin 1 in patients with tobacco-related oral squamous cell carcinoma. Biochem Biophys Res Commun. 422(2):764-769. (IF:2.523)
27. Kapoor V, Zaharieva MM, Das SN, Berger MR (2012). Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma. Cancer Lett. 319: 39-48. (IF: 5.992)